Spielplan
| Wettbewerb | Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|---|
| MLS | 02.04.22 21:30 | 02.04.22 21:30 | Chicago Fire | FC Dallas | 0:0 | 3 - 5 - 5 |
| MLS | 02.04.22 22:00 | 02.04.22 22:00 | Cincinnati FC | CF Montreal | 3:4 | 3 - 5 - 5 |
| MLS | 02.04.22 22:00 | 02.04.22 22:00 | Toronto FC | New York City FC | 2:1 | 4 - 5 - 3 |
| MLS | 03.04.22 00:00 | 03.04.22 00:00 | Columbus Crew | Nashville SC | 0:1 | 3 - 5 - 5 |
| MLS | 03.04.22 01:30 | 03.04.22 01:30 | New England Revolution | New York Red Bulls | 0:1 | 4 - 5 - 4 |
| MLS | 03.04.22 01:30 | 03.04.22 01:30 | Orlando City | Los Angeles FC | 2:4 | 4 - 5 - 4 |
| MLS | 03.04.22 01:30 | 03.04.22 01:30 | San Jose Earthquakes | Austin FC | 2:2 | 4 - 5 - 3 |
| MLS | 03.04.22 01:30 | 03.04.22 01:30 | D.C. United | Atlanta United FC | 0:1 | 3 - 5 - 4 |
| MLS | 03.04.22 01:30 | 03.04.22 01:30 | Philadelphia Union | Charlotte FC | 2:0 | 3 - 5 - 5 |
| MLS | 03.04.22 02:00 | 03.04.22 02:00 | Vancouver Whitecaps | Sporting Kansas City | 1:0 | 4 - 5 - 4 |
| MLS | 03.04.22 02:00 | 03.04.22 02:00 | Minnesota United FC | Seattle Sounders | 1:2 | 4 - 5 - 4 |
| MLS | 03.04.22 02:00 | 03.04.22 02:00 | Inter Miami CF | Houston Dynamo | 1:3 | 4 - 5 - 4 |
| MLS | 03.04.22 03:00 | 03.04.22 03:00 | Colorado Rapids | Real Salt Lake | 1:1 | 4 - 5 - 4 |
| MLS | 03.04.22 22:30 | 03.04.22 22:30 | Portland Timbers | Los Angeles Galaxy | 1:3 | 3 - 5 - 4 |