Spielplan
| Wettbewerb | Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|---|
| MLS | 07.05.22 21:30 | 07.05.22 21:30 | Charlotte FC | Inter Miami CF | 1:0 | 3 - 5 - 5 |
| MLS | 07.05.22 22:00 | 07.05.22 22:00 | CF Montreal | Orlando City | 4:1 | 3 - 5 - 5 |
| MLS | 08.05.22 00:00 | 08.05.22 00:00 | Atlanta United FC | Chicago Fire | 4:1 | 3 - 5 - 5 |
| MLS | 08.05.22 01:00 | 08.05.22 01:00 | New York City FC | Sporting Kansas City | 0:0 | 3 - 5 - 5 |
| MLS | 08.05.22 01:00 | 08.05.22 01:00 | New York Red Bulls | Portland Timbers | 1:1 | 3 - 5 - 5 |
| MLS | 08.05.22 01:30 | 08.05.22 01:30 | New England Revolution | Columbus Crew | 2:2 | 3 - 5 - 5 |
| MLS | 08.05.22 01:30 | 08.05.22 01:30 | D.C. United | Houston Dynamo | 2:0 | 3 - 5 - 5 |
| MLS | 08.05.22 02:00 | 08.05.22 02:00 | Minnesota United FC | Cincinnati FC | 0:1 | 3 - 5 - 5 |
| MLS | 08.05.22 02:30 | 08.05.22 02:30 | FC Dallas | Seattle Sounders | 2:0 | 3 - 5 - 4 |
| MLS | 08.05.22 04:00 | 08.05.22 04:00 | San Jose Earthquakes | Colorado Rapids | 1:0 | 4 - 5 - 4 |
| MLS | 08.05.22 05:00 | 08.05.22 05:00 | Los Angeles FC | Philadelphia Union | 2:2 | 3 - 5 - 5 |
| MLS | 08.05.22 22:00 | 08.05.22 22:00 | Vancouver Whitecaps | Toronto FC | 1:0 | 5 - 5 - 3 |
| MLS | 08.05.22 23:00 | 08.05.22 23:00 | Nashville SC | Real Salt Lake | 2:0 | 3 - 5 - 4 |
| MLS | 09.05.22 01:00 | 09.05.22 01:00 | Austin FC | Los Angeles Galaxy | 0:1 | 4 - 5 - 4 |