Spielplan
| Wettbewerb | Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|---|
| MLS | 17.09.22 19:00 | 17.09.22 19:00 | New York City FC | New York Red Bulls | 2:0 | 3 - 5 - 4 |
| MLS | 17.09.22 21:30 | 17.09.22 21:30 | Atlanta United FC | Philadelphia Union | 0:0 | 4 - 5 - 3 |
| MLS | 18.09.22 01:30 | 18.09.22 01:30 | New England Revolution | CF Montreal | 0:1 | 3 - 5 - 5 |
| MLS | 18.09.22 01:30 | 18.09.22 01:30 | Orlando City | Toronto FC | 4:0 | 3 - 5 - 5 |
| MLS | 18.09.22 02:00 | 18.09.22 02:00 | Chicago Fire | Charlotte FC | 2:3 | 3 - 5 - 4 |
| MLS | 18.09.22 02:30 | 18.09.22 02:30 | Sporting Kansas City | Minnesota United FC | 4:1 | 3 - 5 - 5 |
| MLS | 18.09.22 03:00 | 18.09.22 03:00 | Austin FC | Nashville SC | 1:1 | 3 - 5 - 5 |
| MLS | 18.09.22 03:30 | 18.09.22 03:30 | Real Salt Lake | Cincinnati FC | 1:2 | 3 - 5 - 5 |
| MLS | 18.09.22 04:00 | 18.09.22 04:00 | Vancouver Whitecaps | Seattle Sounders | 2:1 | 4 - 5 - 3 |
| MLS | 18.09.22 04:30 | 18.09.22 04:30 | San Jose Earthquakes | FC Dallas | 1:1 | 4 - 5 - 3 |
| MLS | 18.09.22 04:30 | 18.09.22 04:30 | Los Angeles Galaxy | Colorado Rapids | 4:1 | 3 - 5 - 5 |
| MLS | 18.09.22 19:00 | 18.09.22 19:00 | Columbus Crew | Portland Timbers | 1:1 | 3 - 5 - 5 |
| MLS | 18.09.22 23:00 | 18.09.22 23:00 | D.C. United | Inter Miami CF | 2:3 | 4 - 5 - 3 |
| MLS | 19.09.22 04:30 | 19.09.22 04:30 | Los Angeles FC | Houston Dynamo | 3:1 | 3 - 5 - 5 |