Spielplan
| Wettbewerb | Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|---|
| ESP1 | 11.05.22 19:00 | 11.05.22 19:00 | Deportivo Alaves | Espanyol Barcelona | 2:1 | 1 - 3 - 2 |
| ESP1 | 11.05.22 19:00 | 11.05.22 19:00 | CA Osasuna | FC Getafe | 1:1 | 1 - 2 - 3 |
| FRA1 | 11.05.22 19:00 | 11.05.22 19:00 | OGC Nice | AS St. Etienne | 4:2 | 1 - 3 - 3 |
| ENG1 | 11.05.22 20:30 | 11.05.22 20:30 | Leeds United | FC Chelsea | 0:3 | 3 - 3 - 1 |
| ESP1 | 11.05.22 20:30 | 11.05.22 20:30 | FC Sevilla | RCD Mallorca | 0:0 | 1 - 3 - 3 |
| CH1 | 11.05.22 20:30 | 11.05.22 20:30 | Servette FC Genève | FC Lugano | 2:2 | 1 - 2 - 2 |
| CH1 | 11.05.22 20:30 | 11.05.22 20:30 | FC Sion | FC Luzern | 1:3 | 1 - 2 - 2 |
| Pro | 11.05.22 20:30 | 11.05.22 20:30 | FC Brügge | Royale Union Saint-Gilloise | 1:0 | 1 - 3 - 3 |
| ENG1 | 11.05.22 20:45 | 11.05.22 20:45 | FC Watford | FC Everton | 0:0 | 3 - 3 - 1 |
| ENG1 | 11.05.22 20:45 | 11.05.22 20:45 | Leicester City | Norwich City | 3:0 | 1 - 3 - 3 |
| FRA1 | 11.05.22 21:00 | 11.05.22 21:00 | FC Nantes | Stade Rennes | 2:1 | 3 - 3 - 1 |
| Coppa | 11.05.22 21:00 | 11.05.22 21:00 | Juventus Turin | Inter Mailand | 2:4n.V. | 2 - 3 - 1 |
| ESP1 | 11.05.22 21:30 | 11.05.22 21:30 | FC Elche | Atletico Madrid | 0:2 | 3 - 3 - 1 |
| ESP1 | 12.05.22 19:00 | 12.05.22 19:00 | Real Sociedad | FC Cadiz | 3:0 | 1 - 3 - 3 |
| ESP1 | 12.05.22 20:00 | 12.05.22 20:00 | Rayo Vallecano | FC Villarreal | 1:5 | 3 - 3 - 1 |
| CH1 | 12.05.22 20:30 | 12.05.22 20:30 | FC Zürich | FC Lausanne-Sport | 2:2 | 1 - 3 - 3 |
| CH1 | 12.05.22 20:30 | 12.05.22 20:30 | FC Basel | Grasshopper-Club Zürich | 1:1 | 1 - 3 - 3 |
| Pro | 12.05.22 20:30 | 12.05.22 20:30 | RSC Anderlecht | Royal Antwerp FC | 2:1 | 1 - 3 - 3 |
| ENG1 | 12.05.22 20:45 | 12.05.22 20:45 | Tottenham Hotspur | FC Arsenal | 3:0 | 1 - 2 - 2 |
| ESP1 | 12.05.22 21:30 | 12.05.22 21:30 | Real Madrid | UD Levante | 6:0 | 1 - 3 - 3 |
| PriLi | 13.05.22 21:15 | 13.05.22 21:15 | FC Pacos de Ferreira | Benfica Lissabon | 0:2 | 3 - 3 - 1 |
| 1.BL | 14.05.22 15:30 | 14.05.22 15:30 | VfB Stuttgart | 1. FC Köln | 2:1 | 1 - 2 - 2 |
| 1.BL | 14.05.22 15:30 | 14.05.22 15:30 | Bor. Mönchengladbach | 1899 Hoffenheim | 5:1 | 1 - 3 - 3 |
| 1.BL | 14.05.22 15:30 | 14.05.22 15:30 | 1. FC Union Berlin | VfL Bochum | 3:2 | 1 - 3 - 3 |
| 1.BL | 14.05.22 15:30 | 14.05.22 15:30 | Bayer 04 Leverkusen | SC Freiburg | 2:1 | 1 - 2 - 3 |
| 1.BL | 14.05.22 15:30 | 14.05.22 15:30 | Borussia Dortmund | Hertha BSC | 2:1 | 1 - 3 - 3 |
| 1.BL | 14.05.22 15:30 | 14.05.22 15:30 | Arminia Bielefeld | RB Leipzig | 1:1 | 3 - 3 - 1 |
| 1.BL | 14.05.22 15:30 | 14.05.22 15:30 | FC Augsburg | SpVgg Greuther Fürth | 2:1 | 1 - 3 - 3 |
| 1.BL | 14.05.22 15:30 | 14.05.22 15:30 | FSV Mainz 05 | Eintracht Frankfurt | 2:2 | 1 - 3 - 2 |
| 1.BL | 14.05.22 15:35 | 14.05.22 15:35 | VfL Wolfsburg | FC Bayern München | 2:2 | 3 - 3 - 1 |
| PriLi | 14.05.22 16:30 | 14.05.22 16:30 | CD Tondela | Boavista Porto | 2:2 | 1 - 3 - 2 |
| PriLi | 14.05.22 16:30 | 14.05.22 16:30 | FC Arouca | Belenenses Lissabon | 0:0 | 1 - 2 - 3 |
| PriLi | 14.05.22 16:30 | 14.05.22 16:30 | Moreirense FC | FC Vizela | 4:1 | 1 - 3 - 3 |
| FACup | 14.05.22 17:45 | 14.05.22 17:45 | FC Chelsea | FC Liverpool | 5:6n.E. | 3 - 3 - 1 |
| PriLi | 14.05.22 19:00 | 14.05.22 19:00 | Maritimo Funchal | SC Portimonense | 0:1 | 1 - 2 - 3 |
| PriLi | 14.05.22 19:00 | 14.05.22 19:00 | FC Porto | Estoril Praia | 2:0 | 1 - 3 - 3 |
| PriLi | 14.05.22 21:30 | 14.05.22 21:30 | Sporting Lissabon | CD Santa Clara | 4:0 | 1 - 3 - 3 |
| ENG1 | 15.05.22 13:00 | 15.05.22 13:00 | Tottenham Hotspur | FC Burnley | 1:0 | 1 - 3 - 3 |
| ENG1 | 15.05.22 15:00 | 15.05.22 15:00 | Leeds United | Brighton and Hove Albion | 1:1 | 2 - 2 - 1 |
| ENG1 | 15.05.22 15:00 | 15.05.22 15:00 | Wolverhampton Wanderers | Norwich City | 1:1 | 1 - 3 - 3 |
| ENG1 | 15.05.22 15:00 | 15.05.22 15:00 | West Ham United | Manchester City | 2:2 | 3 - 3 - 1 |
| ENG1 | 15.05.22 15:00 | 15.05.22 15:00 | FC Watford | Leicester City | 1:5 | 3 - 3 - 1 |
| ENG1 | 15.05.22 15:00 | 15.05.22 15:00 | Aston Villa | Crystal Palace | 1:1 | 1 - 2 - 3 |
| ENG1 | 15.05.22 17:30 | 15.05.22 17:30 | FC Everton | Brentford FC | 2:3 | 1 - 3 - 3 |
| PriLi | 15.05.22 19:00 | 15.05.22 19:00 | FC Famalicao | Sporting Braga | 3:2 | 3 - 2 - 1 |
| PriLi | 15.05.22 21:30 | 15.05.22 21:30 | Vitoria Guimaraes | FC Gil Vicente | 5:0 | 1 - 2 - 3 |
| IT1 | 16.05.22 18:30 | 16.05.22 18:30 | Sampdoria Genua | AC Florenz | 4:1 | 3 - 3 - 1 |
| TR1 | 16.05.22 19:00 | 16.05.22 19:00 | Galatasaray Istanbul | Adana Demirspor | 3:2 | 1 - 3 - 3 |
| TR1 | 16.05.22 19:00 | 16.05.22 19:00 | Caykur Rizespor | Sivasspor | 1:2 | 2 - 1 - 1 |
| IT1 | 16.05.22 20:45 | 16.05.22 20:45 | Juventus Turin | Lazio Rom | 2:2 | 1 - 3 - 3 |
| ENG1 | 16.05.22 21:00 | 16.05.22 21:00 | Newcastle United | FC Arsenal | 2:0 | 3 - 3 - 1 |
| RLB | 17.05.22 19:00 | 17.05.22 19:00 | Viktoria Aschaffenburg | 1. FC Schweinfurt 05 | 3:2 | 3 - 3 - 1 |
| ENG1 | 17.05.22 20:45 | 17.05.22 20:45 | FC Southampton | FC Liverpool | 1:2 | 3 - 3 - 1 |
| EL | 18.05.22 21:00 | 18.05.22 21:00 | Eintracht Frankfurt | Glasgow Rangers | 6:5n.E. | 1 - 3 - 3 |
| CH1 | 19.05.22 20:30 | 19.05.22 20:30 | Grasshopper-Club Zürich | FC St.Gallen | 3:2 | 1 - 2 - 2 |
| CH1 | 19.05.22 20:30 | 19.05.22 20:30 | FC Lausanne-Sport | FC Sion | 1:2 | 2 - 2 - 1 |
| CH1 | 19.05.22 20:30 | 19.05.22 20:30 | FC Lugano | FC Zürich | 2:1 | 2 - 2 - 1 |
| CH1 | 19.05.22 20:30 | 19.05.22 20:30 | FC Luzern | Young Boys Bern | 2:2 | 3 - 3 - 1 |
| CH1 | 19.05.22 20:30 | 19.05.22 20:30 | Servette FC Genève | FC Basel | 0:0 | 3 - 3 - 1 |
| Releg | 19.05.22 20:30 | 19.05.22 20:30 | Hertha BSC | Hamburger SV | 0:1 | 2 - 2 - 2 |
| ENG1 | 19.05.22 20:45 | 19.05.22 20:45 | FC Everton | Crystal Palace | 3:2 | 1 - 3 - 3 |
| ENG1 | 19.05.22 21:00 | 19.05.22 21:00 | Aston Villa | FC Burnley | 1:1 | 1 - 3 - 3 |
| ENG1 | 19.05.22 21:00 | 19.05.22 21:00 | FC Chelsea | Leicester City | 1:1 | 1 - 3 - 3 |
| AT1 | 20.05.22 19:00 | 20.05.22 19:00 | Linzer ASK | FC Admira Wacker Mödling | 3:1 | 1 - 3 - 3 |