| Termin | Heim | Gast | Ergebnis |
|---|---|---|---|
| 09.12.25 18:45 | FC Bayern München | Sporting Lissabon | -:- |
| 09.12.25 18:45 | Qairat Almaty | Olympiakos Piräus | -:- |
| 09.12.25 21:00 | AS Monaco | Galatasaray Istanbul | -:- |
| 09.12.25 21:00 | FC Barcelona | Eintracht Frankfurt | -:- |
| 09.12.25 21:00 | PSV Eindhoven | Atletico Madrid | -:- |
| 09.12.25 21:00 | Atalanta Bergamo | FC Chelsea | -:- |
| 09.12.25 21:00 | Tottenham Hotspur | Slavia Prag | -:- |
| 09.12.25 21:00 | Royale Union Saint-Gilloise | Olympique Marseille | -:- |
| 09.12.25 21:00 | Inter Mailand | FC Liverpool | -:- |
| 10.12.25 18:45 | FC Villarreal | FC Kopenhagen | -:- |
| 10.12.25 18:45 | Qarabag | Ajax Amsterdam | -:- |
| 10.12.25 21:00 | Athletic Bilbao | Paris St. Germain | -:- |
| 10.12.25 21:00 | Bayer 04 Leverkusen | Newcastle United | -:- |
| 10.12.25 21:00 | Borussia Dortmund | FK Bodö/Glimt | -:- |
| 10.12.25 21:00 | FC Brügge | FC Arsenal | -:- |
| 10.12.25 21:00 | Juventus Turin | Pafos FC | -:- |
| 10.12.25 21:00 | Real Madrid | Manchester City | -:- |
| 10.12.25 21:00 | Benfica Lissabon | SSC Neapel | -:- |