Spielplan
| Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|
| 04.12.21 13:30 | 04.12.21 13:30 | West Ham United | FC Chelsea | 3:2 | 5 - 3 - 2 |
| 04.12.21 16:00 | 04.12.21 16:00 | Newcastle United | FC Burnley | 1:0 | 2 - 3 - 3 |
| 04.12.21 16:00 | 04.12.21 16:00 | FC Southampton | Brighton and Hove Albion | 1:1 | 3 - 2 - 3 |
| 04.12.21 16:00 | 04.12.21 16:00 | Wolverhampton Wanderers | FC Liverpool | 0:1 | 8 - 6 - 1 |
| 04.12.21 18:30 | 04.12.21 18:30 | FC Watford | Manchester City | 1:3 | 8 - 5 - 1 |
| 05.12.21 15:00 | 05.12.21 15:00 | Leeds United | Brentford FC | 2:2 | 2 - 4 - 5 |
| 05.12.21 15:00 | 05.12.21 15:00 | Manchester United | Crystal Palace | 1:0 | 1 - 5 - 8 |
| 05.12.21 15:00 | 05.12.21 15:00 | Tottenham Hotspur | Norwich City | 3:0 | 1 - 4 - 8 |
| 05.12.21 17:30 | 05.12.21 17:30 | Aston Villa | Leicester City | 2:1 | 3 - 3 - 3 |
| 06.12.21 21:00 | 06.12.21 21:00 | FC Everton | FC Arsenal | 2:1 | 5 - 4 - 1 |