Spielplan
| Wettbewerb | Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|---|
| NFL | 19.11.21 02:20 | 19.11.21 02:18 | Atlanta Falcons | New England Patriots | 0:25 | 5 - 25 Punkte |
| NFL | 21.11.21 19:00 | 21.11.21 18:58 | Chicago Bears | Baltimore Ravens | 13:16 | 5 - 25 Punkte |
| NFL | 21.11.21 19:00 | 21.11.21 18:58 | Minnesota Vikings | Green Bay Packers | 34:31 | 5 - 25 Punkte |
| NFL | 21.11.21 19:00 | 21.11.21 18:58 | Tennessee Titans | Houston Texans | 13:22 | 5 - 25 Punkte |
| NFL | 21.11.21 19:00 | 21.11.21 18:58 | Jacksonville Jaguars | San Francisco 49ers | 10:30 | 5 - 25 Punkte |
| NFL | 21.11.21 19:00 | 21.11.21 18:58 | Cleveland Browns | Detroit Lions | 13:10 | 5 - 25 Punkte |
| NFL | 21.11.21 19:00 | 21.11.21 18:58 | Buffalo Bills | Indianapolis Colts | 15:41 | 5 - 25 Punkte |
| NFL | 21.11.21 19:00 | 21.11.21 18:58 | Carolina Panthers | Washington Football Team | 21:27 | 5 - 25 Punkte |
| NFL | 21.11.21 19:00 | 21.11.21 18:58 | New York Jets | Miami Dolphins | 17:24 | 5 - 25 Punkte |
| NFL | 21.11.21 19:00 | 21.11.21 18:58 | Philadelphia Eagles | New Orleans Saints | 40:29 | 5 - 25 Punkte |
| NFL | 21.11.21 22:05 | 21.11.21 22:03 | Las Vegas Raiders | Cincinnati Bengals | 13:32 | 5 - 25 Punkte |
| NFL | 21.11.21 22:25 | 21.11.21 22:23 | Kansas City Chiefs | Dallas Cowboys | 19:9 | 5 - 25 Punkte |
| NFL | 21.11.21 22:25 | 21.11.21 22:23 | Seattle Seahawks | Arizona Cardinals | 13:23 | 5 - 25 Punkte |
| NFL | 22.11.21 02:20 | 22.11.21 02:18 | Los Angeles Chargers | Pittsburgh Steelers | 41:37 | 5 - 25 Punkte |
| NFL | 23.11.21 02:15 | 23.11.21 02:13 | Tampa Bay Buccaneers | New York Giants | 30:10 | 5 - 25 Punkte |