Spielplan
| Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|
| 28.10.22 02:15 | 28.10.22 02:15 | Tampa Bay Buccaneers | Baltimore Ravens | 22:27 | 5 - 7 - 4 |
| 30.10.22 14:30 | 30.10.22 14:30 | Jacksonville Jaguars | Denver Broncos | 17:21 | 4 - 7 - 6 |
| 30.10.22 18:00 | 30.10.22 18:00 | Dallas Cowboys | Chicago Bears | 49:29 | 4 - 7 - 7 |
| 30.10.22 18:00 | 30.10.22 18:00 | Atlanta Falcons | Carolina Panthers | 37:34OT | 4 - 7 - 6 |
| 30.10.22 18:00 | 30.10.22 18:00 | New York Jets | New England Patriots | 17:22 | 4 - 7 - 5 |
| 30.10.22 18:00 | 30.10.22 18:00 | Detroit Lions | Miami Dolphins | 27:31 | 7 - 7 - 4 |
| 30.10.22 18:00 | 30.10.22 18:00 | Philadelphia Eagles | Pittsburgh Steelers | 35:13 | 4 - 7 - 7 |
| 30.10.22 18:00 | 30.10.22 18:00 | New Orleans Saints | Las Vegas Raiders | 24:0 | 5 - 7 - 4 |
| 30.10.22 18:00 | 30.10.22 18:00 | Minnesota Vikings | Arizona Cardinals | 34:26 | 4 - 7 - 7 |
| 30.10.22 21:05 | 30.10.22 21:05 | Houston Texans | Tennessee Titans | 10:17 | 7 - 7 - 4 |
| 30.10.22 21:25 | 30.10.22 21:25 | Indianapolis Colts | Washington Commanders | 16:17 | 5 - 7 - 5 |
| 30.10.22 21:25 | 30.10.22 21:25 | Seattle Seahawks | New York Giants | 27:13 | 5 - 7 - 5 |
| 30.10.22 21:25 | 30.10.22 21:25 | Los Angeles Rams | San Francisco 49ers | 14:31 | 5 - 7 - 5 |
| 31.10.22 01:20 | 31.10.22 01:20 | Buffalo Bills | Green Bay Packers | 27:17 | 4 - 7 - 7 |
| 01.11.22 01:15 | 01.11.22 01:15 | Cleveland Browns | Cincinnati Bengals | 32:13 | 7 - 7 - 4 |