Spielplan
| Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|
| 24.11.22 18:30 | 24.11.22 18:30 | Detroit Lions | Buffalo Bills | 25:28 | 7 - 7 - 4 |
| 24.11.22 22:30 | 24.11.22 22:30 | Dallas Cowboys | New York Giants | 28:20 | 4 - 7 - 7 |
| 25.11.22 02:20 | 25.11.22 02:20 | Minnesota Vikings | New England Patriots | 33:26 | 4 - 7 - 6 |
| 27.11.22 19:00 | 27.11.22 19:00 | New York Jets | Chicago Bears | 31:10 | 4 - 7 - 6 |
| 27.11.22 19:00 | 27.11.22 19:00 | Washington Commanders | Atlanta Falcons | 19:13 | 4 - 7 - 6 |
| 27.11.22 19:00 | 27.11.22 19:00 | Carolina Panthers | Denver Broncos | 23:10 | 5 - 7 - 5 |
| 27.11.22 19:00 | 27.11.22 19:00 | Jacksonville Jaguars | Baltimore Ravens | 28:27 | 7 - 7 - 4 |
| 27.11.22 19:00 | 27.11.22 19:00 | Miami Dolphins | Houston Texans | 30:15 | 4 - 7 - 7 |
| 27.11.22 19:00 | 27.11.22 19:00 | Cleveland Browns | Tampa Bay Buccaneers | 23:17OT | 7 - 7 - 4 |
| 27.11.22 19:00 | 27.11.22 19:00 | Tennessee Titans | Cincinnati Bengals | 16:20 | 5 - 7 - 5 |
| 27.11.22 22:05 | 27.11.22 22:05 | Seattle Seahawks | Las Vegas Raiders | 34:40OT | 4 - 7 - 7 |
| 27.11.22 22:05 | 27.11.22 22:05 | Arizona Cardinals | Los Angeles Chargers | 24:25 | 6 - 7 - 4 |
| 27.11.22 22:25 | 27.11.22 22:25 | Kansas City Chiefs | Los Angeles Rams | 26:10 | 4 - 7 - 7 |
| 27.11.22 22:25 | 27.11.22 22:25 | San Francisco 49ers | New Orleans Saints | 13:0 | 4 - 7 - 7 |
| 28.11.22 02:20 | 28.11.22 02:20 | Philadelphia Eagles | Green Bay Packers | 40:33 | 4 - 7 - 7 |
| 29.11.22 02:15 | 29.11.22 02:15 | Indianapolis Colts | Pittsburgh Steelers | 17:24 | 4 - 7 - 5 |