Spielplan
| Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|
| 21.10.21 01:30 | 21.10.21 01:25 | Appalachian State Mountaineers | Coastal Carolina Chanticleers | 30:27 | 0 - 3 Punkte |
| 22.10.21 01:30 | 22.10.21 01:25 | Southern Methodist Mustangs | Tulane Green Wave | 55:26 | 0 - 3 Punkte |
| 23.10.21 01:00 | 23.10.21 00:55 | UCF Knights | Memphis Tigers | 24:7 | 0 - 3 Punkte |
| 23.10.21 18:00 | 23.10.21 17:55 | Penn State Nittany Lions | Illinois Fighting Illini | 18:20OT | 0 - 3 Punkte |
| 23.10.21 18:00 | 23.10.21 17:55 | Michigan Wolverines | Northwestern Wildcats | 33:7 | 0 - 3 Punkte |
| 23.10.21 18:00 | 23.10.21 17:55 | Kansas Jayhawks | Oklahoma Sooners | 23:35 | 0 - 3 Punkte |
| 23.10.21 18:00 | 23.10.21 17:55 | Army Black Knights | Wake Forest Demon Deacons | 56:70 | 0 - 3 Punkte |
| 23.10.21 18:00 | 23.10.21 17:55 | Navy Midshipmen | Cincinnati Bearcats | 20:27 | 0 - 3 Punkte |
| 23.10.21 18:00 | 23.10.21 17:55 | Texas Tech Red Raiders | Kansas State Wildcats | 24:25 | 0 - 3 Punkte |
| 23.10.21 21:00 | 23.10.21 20:55 | Purdue Boilermakers | Wisconsin Badgers | 13:30 | 0 - 3 Punkte |
| 23.10.21 21:30 | 23.10.21 21:25 | Ole Miss Rebels | LSU Tigers | 31:17 | 0 - 3 Punkte |
| 23.10.21 21:30 | 23.10.21 21:25 | Pittsburgh Panthers | Clemson Tigers | 27:17 | 0 - 3 Punkte |
| 23.10.21 21:30 | 23.10.21 21:25 | Iowa State Cyclones | Oklahoma State Cowboys | 24:21 | 0 - 3 Punkte |
| 23.10.21 21:30 | 23.10.21 21:25 | UCLA Bruins | Oregon Ducks | 31:34 | 0 - 3 Punkte |
| 23.10.21 21:30 | 23.10.21 21:25 | Minnesota Golden Gophers | Maryland Terrapins | 34:16 | 0 - 3 Punkte |
| 23.10.21 22:00 | 23.10.21 21:55 | Louisville Cardinals | Boston College Eagles | 28:14 | 0 - 3 Punkte |
| 24.10.21 01:00 | 24.10.21 00:55 | Alabama Crimson Tide | Tennessee Volunteers | 52:24 | 0 - 3 Punkte |
| 24.10.21 01:00 | 24.10.21 00:55 | Louisiana Tech Bulldogs | UTSA Roadrunners | 16:45 | 0 - 3 Punkte |
| 24.10.21 01:00 | 24.10.21 00:55 | Air Force Falcons | San Diego State Aztecs | 14:20 | 0 - 3 Punkte |
| 24.10.21 01:00 | 24.10.21 00:55 | Fresno State Bulldogs | Nevada Wolf Pack | 34:32 | 0 - 3 Punkte |
| 24.10.21 01:30 | 24.10.21 01:25 | Texas A&M Aggies | South Carolina Gamecocks | 44:14 | 0 - 3 Punkte |
| 24.10.21 01:30 | 24.10.21 01:25 | Miami (FL) Hurricanes | North Carolina State Wolfpack | 31:30 | 0 - 3 Punkte |
| 24.10.21 01:30 | 24.10.21 01:25 | Indiana Hoosiers | Ohio State Buckeyes | 7:54 | 0 - 3 Punkte |
| 24.10.21 01:30 | 24.10.21 01:25 | Notre Dame Fighting Irish | USC Trojans | 31:16 | 0 - 3 Punkte |
| 24.10.21 01:30 | 24.10.21 01:25 | TCU Horned Frogs | West Virginia Mountaineers | 17:29 | 0 - 3 Punkte |