Spielplan
| Wettbewerb | Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|---|
| MLS | 19.03.22 18:00 | 19.03.22 18:00 | New York City FC | Philadelphia Union | 0:2 | 3 - 5 - 5 |
| MLS | 19.03.22 18:00 | 19.03.22 18:00 | Cincinnati FC | Inter Miami CF | 3:1 | 4 - 5 - 4 |
| MLS | 19.03.22 20:00 | 19.03.22 20:00 | Toronto FC | D.C. United | 2:1 | 3 - 5 - 4 |
| MLS | 19.03.22 20:30 | 19.03.22 20:30 | Los Angeles Galaxy | Orlando City | 0:1 | 3 - 5 - 5 |
| MLS | 19.03.22 21:00 | 19.03.22 21:00 | Atlanta United FC | CF Montreal | 3:3 | 3 - 5 - 5 |
| MLS | 19.03.22 23:00 | 19.03.22 23:00 | Chicago Fire | Sporting Kansas City | 3:1 | 3 - 5 - 5 |
| MLS | 20.03.22 00:00 | 20.03.22 00:00 | Charlotte FC | New England Revolution | 3:1 | 5 - 5 - 3 |
| MLS | 20.03.22 01:00 | 20.03.22 01:00 | Minnesota United FC | San Jose Earthquakes | 1:0 | 3 - 5 - 5 |
| MLS | 20.03.22 01:30 | 20.03.22 01:30 | FC Dallas | Portland Timbers | 4:1 | 4 - 5 - 3 |
| MLS | 20.03.22 01:30 | 20.03.22 01:30 | Houston Dynamo | Colorado Rapids | 1:1 | 5 - 5 - 3 |
| MLS | 20.03.22 02:30 | 20.03.22 02:30 | Real Salt Lake | Nashville SC | 2:1 | 3 - 5 - 5 |
| MLS | 20.03.22 19:00 | 20.03.22 19:00 | New York Red Bulls | Columbus Crew | 1:1 | 3 - 5 - 5 |
| MLS | 20.03.22 21:30 | 20.03.22 21:30 | Austin FC | Seattle Sounders | 1:1 | 5 - 5 - 3 |
| MLS | 21.03.22 03:00 | 21.03.22 03:00 | Los Angeles FC | Vancouver Whitecaps | 3:1 | 3 - 5 - 5 |