Spielplan
| Wettbewerb | Termin | Tipptermin | Heim | Gast | Ergebnis | Punkteregel |
|---|---|---|---|---|---|---|
| MLS | 21.05.22 21:30 | 21.05.22 21:30 | Columbus Crew | Los Angeles FC | 0:2 | 4 - 5 - 3 |
| MLS | 22.05.22 00:00 | 22.05.22 00:00 | Cincinnati FC | New England Revolution | 2:3 | 4 - 5 - 4 |
| MLS | 22.05.22 00:30 | 22.05.22 00:30 | D.C. United | Toronto FC | 2:2 | 3 - 5 - 5 |
| MLS | 22.05.22 01:30 | 22.05.22 01:30 | Nashville SC | Atlanta United FC | 2:2 | 4 - 4 - 4 |
| MLS | 22.05.22 22:00 | 22.05.22 22:00 | CF Montreal | Real Salt Lake | 1:2 | 3 - 5 - 5 |
| MLS | 22.05.22 23:00 | 22.05.22 23:00 | New York City FC | Chicago Fire | 1:0 | 3 - 5 - 5 |
| MLS | 22.05.22 23:00 | 22.05.22 23:00 | Charlotte FC | Vancouver Whitecaps | 2:1 | 3 - 5 - 5 |
| MLS | 23.05.22 00:00 | 23.05.22 00:00 | Inter Miami CF | New York Red Bulls | 2:0 | 4 - 5 - 3 |
| MLS | 23.05.22 01:00 | 23.05.22 01:00 | FC Dallas | Minnesota United FC | 1:2 | 3 - 5 - 5 |
| MLS | 23.05.22 01:30 | 23.05.22 01:30 | San Jose Earthquakes | Sporting Kansas City | 1:1 | 3 - 5 - 5 |
| MLS | 23.05.22 02:00 | 23.05.22 02:00 | Los Angeles Galaxy | Houston Dynamo | 0:3 | 3 - 5 - 5 |
| MLS | 23.05.22 02:00 | 23.05.22 02:00 | Colorado Rapids | Seattle Sounders | 1:0 | 4 - 5 - 3 |
| MLS | 23.05.22 02:00 | 23.05.22 02:00 | Austin FC | Orlando City | 2:2 | 3 - 5 - 5 |
| MLS | 23.05.22 04:00 | 23.05.22 04:00 | Portland Timbers | Philadelphia Union | 0:2 | 4 - 5 - 4 |